Nur Annisa*, Rini Hendriani**, Ahmad Muhtadi***



 Diabetes mellitus is one of the leading causes of world death. This disease has the highest prevalence of death in Indonesia in Southeast Asia. Diabetes mellitus is mostly found in men patients as much as 60%. Currently, there are various kinds of antidiabetic drugs that have been circulating in the market and consumed by humans. Unfortunately, the drugs that have been circulating it still has a considerable shortage of side effects. Thus, researchers are still looking for and developing new drugs. In addition, many people turn to alternative medicine. In addition, traditional medicine also has advantages such as side effects that are so small that many people turn to traditional medicine. One of the plants that can play a role in antidiabetic is Amaryllidaceae. In the last 10 years there are known to be 9 species in the Amaryllidaceae that have potential in antidiabetic activity with secondary metabolite compounds in the form of alkaloid and flavonoid that play a role in decreasing blood sugar levels in the body. The 3 best candidates are on the Galanthus reginae-olgae subsp plant. vernalis, Allium cepa L., and Zephyranthes candida (Lindl.) Herb. All of the genera belonging to this Amaryllidaceae whose existence of habitat in Asia is the genera of Allium and these genera belong to category 3 of the best candidate. So that other species contained within this genera can be studied and developed in Indonesia.


Keywords: Diabetes Mellitus, Anti-diabetic, Medicine plant, Amaryllidaceae


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